Mapping a shared genetic basis for neurodevelopmental disorders
نویسندگان
چکیده
منابع مشابه
Cure neurodevelopmental genetic disorders, please.
Dramatic, seemingly exponential advances have brought about much hope towards improving the efficacy of management of patients with conditions long-thought incurable, such as neurogenetic disorders. These advances have been both technological and conceptual. They result from refinements in the understanding of pathophysiology and intensive developments of approaches to compensate or bypass the ...
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Neurodevelopmental disorders (NDs) are currently thought to be caused by either genetic defects or various environmental factors. Recent studies have demonstrated that congenital NDs can result not only from changes in DNA sequence in neuronal genes but also from changes to the secondary epigenomic modifications of DNA and histone proteins. Thus, epigenomic assays, as well as genomic assays, ar...
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ژورنال
عنوان ژورنال: Genome Medicine
سال: 2017
ISSN: 1756-994X
DOI: 10.1186/s13073-017-0503-4